Search on: PIT-OCT-UNC PROTEINS 
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Descriptor English:   POU Domain Factors 
Descriptor Spanish:   Factores del Dominio POU 
Descriptor Portuguese:   Fatores do Domínio POU 
Synonyms English:   POU Proteins
Pit-Oct-Unc Proteins
Transcription Factor POU
POU, Transcription Factor
Pit Oct Unc Proteins  
Tree Number:   D12.776.260.655
D12.776.930.710
Definition English:   A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors. 
History Note English:   2006(1992) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   51034 
Unique Identifier:   D050809 

Occurrence in VHL:
 

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